Methods, systems, and apparati for cellular therapeutic...

A - Human Necessities – 61 – M

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A61M 1/02 (2006.01)

Patent

CA 2720901

Methods and devices for the preparation of a biological pharmaceutical composition outside of a classified environment, such as Biological Safety Cabinet type environment, are described. In one aspect of the present technology, a method is provided to prepare a biological pharmaceutical composition preferably in an area next to a patient's bedside or at a facility's pharmacy. The method comprises transferring an appropriate amount of a diluent from a diluent component (645) into a mixing receptacle (605) using a transfer device (620), connecting a pooling (630) harness between a.biological pharmaceutical component (640) and the mixing receptacle, transferring a biological pharmaceutical composition through the pooling harness to the mixing receptacle, mixing the diluent and the biological pharmaceutical composition to form a biological pharmaceutical composition mixture and administering the biological pharmaceutical composition mixture to a patient for either flat based or weight based dosing needs.

Cette invention concerne des procédés et des dispositifs pour la préparation d'une composition pharmaceutique biologique en dehors d'un environnement classé, tel qu'un environnement du type Poste de sécurité biologique. Selon un aspect de la présente technologie, un procédé permet de préparer une composition pharmaceutique biologique, de préférence dans une zone proche du chevet dun patient ou à la pharmacie dune infrastructure. Le procédé comprend les étapes consistant à transférer une quantité appropriée d'un diluant à partir d'un composant diluant (645) dans un réceptacle de mélange (605) au moyen d'un dispositif de transfert (620), à connecter un harnais de groupage (630) entre un composant pharmaceutique biologique (640) et le réceptacle de mélange, à transférer dans le réceptacle de mélange la composition pharmaceutique biologique via le harnais de groupage, à mélanger le diluant et la composition pharmaceutique biologique pour former un mélange de composition pharmaceutique biologique et à administrer le mélange de composition pharmaceutique biologique à un patient en vue de répondre à des besoins de dosage soit à base fixe soit à base du poids.

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