Niosome-hydrogel drug delivery

Details Niosome-hydrogel drug delivery Niosome-hydrogel drug delivery

A - Human Necessities

61

K

A61K 9/10 (2006.01) A61K 9/127 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2649900

Taught herein is a drug-delivery system that includes encapsulating a therapeutic drug in a nanoparticle vesicle that is then embedded into a hydrogel network. The system allows for enhanced, two-fold control over the release rate of the drug. This technology will be particularly advantageous in treating malignant cancer cells such as those found in the brain. The invention will allow for decreased side effects and increased survival time in patients. This invention opens the door to other technological applications that require controlled release of chemical substances.

L'invention concerne un mode d'administration de médicaments comprenant l'encapsulation d'un agent thérapeutique dans une vésicule de la taille d'une nanoparticule, qui est intégrée dans un réseau hydrogel. Le mode d'administration permet un double contrôle amélioré de la vitesse de libération du médicament. De manière avantageuse, cette technologie peut être utilisée dans le traitement de cellules cancéreuses malignes, telles que celles présentes dans le cerveau. L'invention est caractérisée en ce que les effets secondaires diminuent et la durée de vie est amélioré chez les patients. L'invention ouvre la voie à des applications technologiques qui nécessitent une libération contrôlée de substances chimiques.

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