Transmucosal composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/38 (2006.01) A61K 9/70 (2006.01) A61K 47/32 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2650040

The invention provides a composition for delivering active agents through transmucosal administration, more particularly through the buccal mucosa. The composition is a unique transmucosal disk (10) which has two compartments (14) and (18); the compartments consist of at least one active agent and at least one mucoadhesive agent and both the compartments are adapted to be in contact with the mucosal membrane. The invention also provides for transmucosal administration of an active agent and method of treatment of diseases in a subject in need of such treatment.

La présente invention concerne une composition permettant la libération de principes actifs par administration transmucosale, plus particulièrement au travers de la muqueuse buccale. La composition est constituée d'un unique disque transmucosal composé de deux compartiments; les compartiments sont constitués d'au moins un principe actif et d'au moins un agent muco-adhésif, et les deux compartiments sont adaptés à un contact avec la membrane muqueuse. La présente invention concerne également une méthode d'administration transmucosale d'un principe actif et une méthode de traitement de maladies chez un sujet nécessitant un tel traitement.

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