Fused bicyclic pyrimidine derivatives

Details Fused bicyclic pyrimidine derivatives Fused bicyclic pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/505 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2272705

The invention relates to compounds of formula (I) and to pharmaceutically acceptable salts thereof, wherein R1, R2 and Z are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula (I) and to methods of using said compounds in the treatment of hyperproliferative diseases such as cancer.

Cette invention se rapporte à des composés représentés par la formule (I) et à sels de ces composés acceptables sur le plan pharmaceutique, formule dans laquelle R?1¿, R?2¿ et Z sont définis dans les pièces descriptives de l'invention. Cette invention se rapporte également à des compositions pharmaceutiques contenant ces composés de la formule (I) et à des procédés d'utilisation de ces composés dans le traitement de maladies hyperprolifératives, tel que le cancer.

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