Method for reducing sepsis or cardiogenic shock associated...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2609071

Methods of reducing sepsis or cardiogenic shock in patients experiencing myocardial injury are described. More specifically, this disclosure relates to the administration of a C5-C9 terminal complement inhibitor to patients who have had coronary artery bypass grafting or an acute myocardial infarction thereby reducing the incidence of sepsis.

Cette invention concerne des procédés permettant de réduire un choc septique ou cardiogène chez des patients souffrant d'une lésion du myocarde. Plus spécifiquement, cette invention concerne l'administration d'un inhibiteur de complément de terminaison C5-C9 à des patients ayant subi un pontage aortocoronarien ou un infarctus du myocarde aigu, réduisant ainsi l'incidence d'une septicémie.

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