Mammalian expression systems for hepatitis c virus envelope...

Details Mammalian expression systems for hepatitis c virus envelope... Mammalian expression systems for hepatitis c virus envelope...

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 39/29 (2006.01) C07K 14/18 (2006.01) C07K 14/47 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) G01N 33/576 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2182170

Mammalian expression systems for the production of HCV E1-E2 fusion proteins. Such expression systems provide high yields of HCV proteins extracellularly and enable the development of diagnostic, vaccine and therapeutic reagents which contain glycosylated structural antigens and also allow for the isolation of the HCV etiological agent.

Systèmes d'expression mammaliens pour la production de protéines de fusion E1-E2 du VHC. Lesdits systèmes d'expression permettent d'obtenir de grandes quantités de protéines de VHC extracellulairement, permettent le développement de réactifs diagnostiques, pour vaccins et thérapeutiques qui contiennent des antigènes structuraux glycosylés et permettent également l'isolation de l'agent étiologique du VHC.

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