Piperidyl benzamide compounds, composition containing same...

Details Piperidyl benzamide compounds, composition containing same... Piperidyl benzamide compounds, composition containing same...

C - Chemistry, Metallurgy

07

D

C07D 211/58 (2006.01) A61K 31/445 (2006.01) A61K 31/496 (2006.01) A61P 25/28 (2006.01) C07C 275/00 (2006.01) C07D 211/96 (2006.01) C07D 213/75 (2006.01) C07D 295/18 (2006.01) C07D 295/20 (2006.01) C07D 295/22 (2006.01) C07D 295/26 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2360360

This invention relates to new amide compounds having the potentiation of the cholinergic activity, etc., and represented by general formula (I), wherein R1 is acyl, R2 is lower alkyl, etc., A is a single bond, (1) or -SO2-, E is lower alkylene, etc., X is CH or N, Y is a single bond, etc., Q is -CH2-, etc., and R3 and R4 are taken together to form lower alkylene, etc., and pharmaceutically acceptable salts thereof, to processes for preparation thereof and a pharmaceutical composition comprising the same.

L'invention concerne de nouveaux composés amide permettant la potentialisation de l'activité cholinergique, etc., et représentés par la formule (I). Dans cette formule, R<1> représente acyle, R<2> représente alkyle inférieur, etc., A représente une liaison simple, (1) ou -SO2-, E représente alkylène inférieur, etc., X représente CH ou N, Y représente une liaison simple, etc., Q représente -CH2-, etc., et R<3> et R<4> sont pris ensemble pour former alkylène inférieur, etc. L'invention concerne également des sels pharmaceutiquement acceptables desdits composés, des techniques de préparation de ces composés et une composition pharmaceutique comprenant ces composés.

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