Novel steroid esters

C - Chemistry – Metallurgy – 07 – J

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C07J 71/00 (2006.01) A61K 31/58 (2006.01)

Patent

CA 2100453

2100453 9213873 PCTABS00014 Compounds of general formula (I), in which formula the 1,2-position is satured or is a double bond, R1 is hydrogen or a straight or branched hydrocarbon chain, R2 is a hydrogen or a straight or branched hydrocarbon chain, R3 is acyl, X1 is hydrogen or halogen, X2 is hydrogen or halogen and provided that 1) R1 and R2 are not simultaneously hydrogen, 2) X1 and X2 are not simultaneously hydrogen, 3) when the 1,2-position is a double bonnd, R1 and R2 are not simultaneously methyl groups, 4) when the 1,2-position is a double bond, R1 is a hydrogen atom and R2 is a straight or branched hydrocarbon chain having 1-10 carbon atoms R3 is acyl having 11-20 carbon atoms, processes for their preparation, pharmaceutical preparations containing them and the use of the compounds in the treatment of inflammatory and allergic conditions.

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