Uterine fibroid treatment

Details Uterine fibroid treatment Uterine fibroid treatment

A - Human Necessities

61

K

A61K 38/09 (2006.01) A61K 31/00 (2006.01) A61K 31/40 (2006.01) A61K 31/4178 (2006.01) A61K 31/437 (2006.01) A61K 38/05 (2006.01) A61K 38/08 (2006.01) A61K 38/55 (2006.01)

Patent

CA 2192061

The use of a) an angiotensin-converting enzyme (ACE) inhibitor such as Captopril or Enalapril, b) an angiotensin II-receptor antagonist such as Saralasin or Losartan, or c) a renin inhibitor, such as Remikiren or [N- (pyridyl-3-propionyl)-phenylalanyl-histidyl-(3S,4S) ACHPA-isoleucylamino]-2- methyl-2-dihydroxy-1,3-propane, for the manufacture of a medicament for the treatment of uterine fibroids is disclosed. The ACE inhibitor may be used concomitantly or sequentially with a gonadotropin-releasing hormone agonist such as Buserelin or Goserelin.

L'invention se rapporte à (a) un inhibiteur de l'enzyme de conversion de l'angiotensine, tel que Captopril ou Enalapril, (b) un antagoniste du récepteur de l'angiotensine II, tel que Saralasin ou Losartan, ou (c) un inhibiteur de la rénine, tel que Remikiren ou [N-(pyridil-3-propionyl)-phénylalanyl-histidyl-(3S,4S) ACHPA-isoleucylamino]-2-méthyl-2-dihydroxy-1,3-propane qui sont utilisés dans la fabrication d'un médicament en vue traiter les fibromes utérins. L'inhibiteur de l'enzyme de conversion de l'angiotensine peut être utilisé simultanément ou séquentiellement avec un agoniste de l'hormone libérant la gonadotropine, tel que Buséréline ou Goséréline.

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