Preparation of mhc-peptide complexes

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/74 (2006.01) A61K 39/385 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2201519

The present invention provides methods for preparing MHC-peptide complexes of defined composition. The methods use large molar excesses of peptide. Alternatively, the methods use optimized pH conditions.

La présente invention concerne des procédés pour préparer des complexes peptide/système majeur d'histocompatibilité ayant une composition définie. Le peptides sont utilisés en fort excès molaire. On peut également optimiser le pH de préparation.

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