Sulfur substituted aryldifluoromethylphosphonic acids as...

Details Sulfur substituted aryldifluoromethylphosphonic acids as... Sulfur substituted aryldifluoromethylphosphonic acids as...

C - Chemistry, Metallurgy

07

F

C07F 9/38 (2006.01) A61K 31/66 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07F 9/40 (2006.01) C07F 9/553 (2006.01) C07F 9/58 (2006.01) C07F 9/59 (2006.01) C07F 9/60 (2006.01) C07F 9/6506 (2006.01) C07F 9/6512 (2006.01) C07F 9/6518 (2006.01) C07F 9/6524 (2006.01) C07F 9/653 (2006.01) C07F 9/6539 (2006.01) C07F 9/655 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 2402414

The invention encompasses the novel class of compounds represented by the formula (I), which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes.

L'invention concerne une nouvelle classe de composés représentée par la formule (I), qui sont des inhibiteurs de l'enzyme PTP-1B. L'invention concerne également des préparations pharmaceutiques et des procédés de traitement ou de prévention des affections causées par la PTP-1B, affections comprenant le diabète.

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