C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/24 (2006.01) A61K 31/216 (2006.01) A61P 25/28 (2006.01) C07D 401/04 (2006.01) C07D 407/04 (2006.01) C07D 409/04 (2006.01)
Patent
CA 2731190
The present invention relates to compounds of Formula I as shown below, wherein the definitions of A, X, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with .gamma.-secretase activity, including Alzheimer's disease.
La présente invention concerne des composés de formule (I) présentée ci-dessous, les définitions de A, X, R1 R2, R3, R4, R5, R6, R7, R8, et R9 étant données dans la description. Les composés de formule I sont utiles pour le traitement de maladies associées à une activité ?-sécrétase notamment la maladie d'Alzheimer.
Lu Tianbao
Janssen Pharmaceutica Nv
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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