Isolated post-translationally modified proteins for...

C - Chemistry – Metallurgy – 07 – K

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Details

C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2501756

Isolated phosphorylated troponin I proteins useful in diagnosing and monitoring the phosphorylation state of injured muscle tissue are provided. Also provided are compounds, kits and methods for assessing the phosphorylation state of these troponin I proteins and modulating the phosphorylation state of these troponin I proteins in a subject.

La présente invention concerne des protéines de troponine I phosphorylées isolées utiles pour diagnostiquer et suivre l'état de phosphorylation de tissus musculaires lésés. L'invention a également pour objet des composés, des kits et des procédés pour évaluer l'état de phosphorylation de ces protéines de troponine I et moduler l'état de phosphorylation de ces protéines de troponine I chez une personne.

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