Preparation of derivatives of 6-trifluoromethyl-1,3,5-triazine

C - Chemistry – Metallurgy – 07 – D

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C07D 251/22 (2006.01) C07D 251/16 (2006.01)

Patent

CA 2081413

Abstract of the Disclosure: 6-Trifluoromethyl-1,3,5- triazines I Image where R 1 is H and R 1 and R 2 are each a C-organic radical, are prepared by reacting a salt of an N-amidino-S-alkyl- isothiourea II Image where R 3 is a C-organic radical of 1 to 10 carbon atoms, with a trifluoroacetic acid derivative III and a strong base IV to give a 6-trifluoromethyl-1,3,5-triazine V Image and reacting the product V in the presence of a base with an alcohol VII R 2-OH VII. The triazines I are useful intermediates for crop protection agents.

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