Pyridine and pyrimidine derivatives as mglur2 antagonists

Details Pyridine and pyrimidine derivatives as mglur2 antagonists Pyridine and pyrimidine derivatives as mglur2 antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/4427 (2006.01) A61K 31/506 (2006.01) A61P 25/00 (2006.01) C07D 401/14 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2681733

The present invention relates to compounds of formula (I), a process for the manufacture thereof, their use for the preparation of medicaments for treating CNS disorders and pharmaceutical compositions containing them. Compounds of formula (I) are represented by general formula (I) wherein Q, A, B, X, Y, R 1 and R 2 are defined as in the specification.

La présente invention porte sur des composés de formule (I), sur un procédé de fabrication de ces composés, sur leur utilisation pour la préparation de médicaments traitant des troubles du système nerveux central, et sur des compositions pharmaceutiques les contenant. Les composés de formule (I) sont représentés par la formule générale (I), dans laquelle Q, A, B, X, Y, R1 et R2 sont tels que définis dans la description.

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