C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/14 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61K 31/421 (2006.01) A61K 31/426 (2006.01) A61K 31/4427 (2006.01) A61P 37/06 (2006.01) C07D 263/34 (2006.01) C07D 277/20 (2006.01) C07D 307/68 (2006.01) C07D 333/40 (2006.01) C07D 405/12 (2006.01) C07D 409/00 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2639913
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein R1, X1, X2, Y, Z, L, and n are defined herein. The compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
La présente invention concerne des composés de formule structurelle (I), dans laquelle: R1, X1, X2, Y, Z, L, et n sont tels que définis dans la description, ou un sel, un solvate, un clathrate, ou promédicament pharmaceutiquement acceptable de ces composés. Les composés sont utiles en tant qu'agents immunosuppresseurs et pour le traitement de maladies inflammatoires, de troubles allergiques, et de troubles immunitaires.
Chen Shoujun
Jiang Jun
Vo Nha Huu
Zhang Junyi
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Synta Pharmaceutical Corp.
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