Immunoglobulin conjugates of autoantigens and their use in...

Details Immunoglobulin conjugates of autoantigens and their use in... Immunoglobulin conjugates of autoantigens and their use in...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01)

Patent

CA 2524615

Conjugates comprising a disease-relevant autoantigen (proinsulin protein chain) and an isologous immunoglobulin are disclosed. Such conjugates demonstrate efficacy in the treatment of autoimmune diseases, such as type I diabetes.

L'invention concerne des conjugués comprenant un autoantigène correspondant à une maladie (chaîne protéique de la proinsuline) ainsi qu'une immunoglobuline isologue. De tels conjugués font preuve d'efficacité dans le traitement de maladies auto-immunes telles que le diabète de type I.

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