Substituted indolyl and indazolyl derivatives and uses thereof

Details Substituted indolyl and indazolyl derivatives and uses thereof Substituted indolyl and indazolyl derivatives and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 209/08 (2006.01) A61K 31/404 (2006.01) A61K 31/416 (2006.01) A61K 31/4178 (2006.01) A61K 31/435 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 209/30 (2006.01) C07D 209/42 (2006.01) C07D 231/56 (2006.01) C07D 401/06 (2006.01) C07D 403/10 (2006.01) C07D 413/10 (2006.01) C07D 417/10 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2730397

This application discloses compounds of generic Formula I':or pharmaceutically acceptable salts thereof, wherein A, Q, X, Y, Z1, Z2, m, p, q, z, R1, R1', R2, R3 and R4 are defined as described herein, useful for treatment of diseases associated with monoamine deficiency. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.

Cette invention porte sur des composés de formule générique I' : ou sur des sels pharmaceutiquement acceptables correspondants, dans laquelle formule A, Q, X, Y, Z1, Z2, m, p, q, z, R1, R1', R2, R3 et R4 sont tels que définis dans la description, utiles pour le traitement de maladies associées à une déficience de monoamine. L'invention porte également sur des compositions pharmaceutiques, des procédés d'utilisation et des procédés de préparation des composés.

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