A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 35/14 (2006.01)
Patent
CA 2263911
An autoimmune vaccine is provided for administration to human patients to alleviate the symptoms of autoimmune diseases such as rheumatoid arthritis. The vaccine comprises an aliquot of the patient's blood, containing, inter alia , leukocytes having upregulated expression of various cell surface markers and lymphocytes containing decreased amounts of certain stress proteins. It is produced by subjecting the blood aliquot extracorporeally to certain stressors, namely oxidizing agents, UV radiation and elevated temperature.
L'invention concerne un vaccin auto-immune destiné à être administré à des patients humains afin d'atténuer les symptômes de maladies auto-immunes telles que la polyarthrite rhumatoïde. Le vaccin comprend un aliquote du sang du patient, contenant entre autres des leucocytes dans lesquels l'expression de divers marqueurs de la surface cellulaire est régulée positivement, et des lymphocytes qui contiennent des quantités réduites de certaines protéines de stress. On fabrique le vaccin en soumettant l'aliquote de sang, en extracorporel, à certains agents stressants, à savoir des agents oxydants, un rayonnement UV et une température élevée.
Ridout & Maybee Llp
Vasogen Inc.
Vasogen Ireland Limited
LandOfFree
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