Stable lansoprazole formulation

Details Stable lansoprazole formulation Stable lansoprazole formulation

A - Human Necessities

61

K

A61K 9/58 (2006.01) A61K 31/4439 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2543172

A stable composition comprising a substrate comprising lansopraxole (preferably in the base form), without any alkaline agent; a subcoating layer containing alkaline agent; and an enteric coating layer. The substrate is preferably as inert core with an active layer (containing lansopraxole) layered over it.

L'invention décrit une composition stable contenant un substrat qui renferme du lansoprazole (de préférence sous sa forme de base) mais qui est dépourvu de tout agent alcalin; une couche de sous-revêtement contenant un agent alcalin; ainsi qu'une couche de revêtement gastro-résistant. De préférence, ce substrat est un noyau inerte recouvert d'une couche active (contenant du lansopraxole).

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