Substituted phenylamidines, pharmaceutical compositions...

Details Substituted phenylamidines, pharmaceutical compositions... Substituted phenylamidines, pharmaceutical compositions...

C - Chemistry, Metallurgy

07

D

C07D 211/34 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/27 (2006.01) A61K 31/275 (2006.01) A61K 31/395 (2006.01) C07C 257/18 (2006.01) C07D 207/09 (2006.01) C07D 223/04 (2006.01) C07D 241/08 (2006.01) C07D 243/08 (2006.01) C07D 295/15 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01)

Patent

CA 2219337

The present invention relates to phenyl amidines of general formula (I), in which R1 to R5 are as defined in claim 1, their tautomers, their stereoisomers and their mixtures and their salts, especially their physiologically acceptable salts with inorganic or organic acids or bases also having valuable pharmacological properties, preferably aggregation-limiting effects. The invention also relates to medicaments containing these compounds, their use and a process for producing them.

L'invention concerne des phénylamidines de la formule générale (I) dans laquelle R?1¿ à R?5¿ correspondent à la définition donnée dans la revendication 1, leurs tautomères, leurs stéréoisomères de même que leurs mélanges et leurs sels, notamment leurs sels physiologiquement tolérables avec des acides ou des bases organiques ou inorganiques, qui présentent entre autres des propriétés pharmacologiques précieuses, de préférence des effets inhibant l'agrégation. L'invention concerne en outre des médicaments contenant lesdits composés, leur utilisation et des procédés permettant de les préparer.

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