A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 48/00 (2006.01) A61K 47/42 (2006.01)
Patent
CA 2492089
The present invention relates to a delivery system for pharmaceutical agents. Said delivery system comprises liposomes which comprise in their internal compartment a pharmaceutical agent to be delivered and which have linked to their external surface the cell adhesion molecule NCAM or a fragment thereof. In a preferred embodiment said pharmaceutical agent is a DNA, pre ferably a cDNA which is operably linked to a gene expression construct.
La présente invention concerne un système d'apport d'agents pharmaceutiques. Ledit système d'apport comprend des liposomes qui renferment, dans leur compartiment interne, un agent pharmaceutique devant être apporté et qui sont liés sur leur surface extérieure, à la molécule d'adhésion de cellules NCAM ou à un fragment de cette dernière. Dans une forme de réalisation préférée, ledit agent pharmaceutique est un ADN, de préférence un ADNc qui est fonctionnellement lié à une construction d'expression génique.
Bcf Llp
Bron Denis
LandOfFree
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