C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/14 (2006.01) A61K 31/4025 (2006.01) A61P 7/02 (2006.01) C07D 207/12 (2006.01) C07D 207/14 (2006.01) C07D 207/16 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2604603
The invention is concerned with novel cyclic amines of formula (I) wherein X1 to X3, Y1 to Y3, R1~ , R1~~ and n are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.
L'invention concerne de nouvelles amines cycliques ayant la formule (I) dans laquelle X1 à X3, Y1 à Y3, R1', R1'' et n sont définis dans la description et les revendications ainsi que leurs sels physiologiquement acceptables. Ces composés inhibent le facteur de coagulation Xa et peuvent s'utiliser en tant que médicaments.
Groebke-Zbinden Katrin
Haap Wolfgang
Hilpert Hans
Panday Narendra
Ricklin Fabienne
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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