Golfomycin derivatives: novel fused ring cyclodecadiyne...

Details Golfomycin derivatives: novel fused ring cyclodecadiyne... Golfomycin derivatives: novel fused ring cyclodecadiyne...

C - Chemistry, Metallurgy

07

C

C07C 49/755 (2006.01) A61K 31/12 (2006.01) A61K 31/33 (2006.01) A61K 31/66 (2006.01) C07C 45/29 (2006.01) C07C 45/67 (2006.01) C07C 47/56 (2006.01) C07C 49/747 (2006.01) C07C 69/013 (2006.01) C07C 69/03 (2006.01) C07C 69/68 (2006.01) C07C 205/45 (2006.01) C07D 221/04 (2006.01) C07D 239/70 (2006.01) C07D 241/36 (2006.01) C07D 263/52 (2006.01) C07D 307/93 (2006.01) C07D 333/78 (2006.01) C07F 9/117 (2006.01)

Patent

CA 2088498

2088498 9202480 PCTABS00010 5-Hydroxy-benzo-(1',2')-cyclodeca-2,7-diyne-1-one and derivatives thereof and related fused ring diyneone macrocyclic compounds are disclosed. The compounds possess DNA-cleaving, antibiotic and tumor growth-inhibiting properties. Methods of making and using the same are also disclosed.

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