4-aminopiperidine derivatives

Details 4-aminopiperidine derivatives 4-aminopiperidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 211/58 (2006.01) A61K 31/4468 (2006.01) A61K 31/45 (2006.01) C07D 211/60 (2006.01) C07D 277/04 (2006.01)

Patent

CA 2590957

The present invention relates to compounds of the formula (I), wherein R1 and R2 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/ or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, non-insulin dependent diabetes mellitus and/or impaired glucose tolerance, obesity, and/or metabolic syndrome or ~-cell protection.

La présente invention concerne des composés représentés par la formule (I), dans laquelle R1 et R2 sont comme définis dans le descriptif et dans les revendications, ainsi que des sels pharmaceutiquement acceptables de ces composés. Lesdits composés conviennent pour le traitement et/ou la prophylaxie de pathologies associées à la DPP-IV, telles que le diabète, le diabète sucré non insulino-dépendant et/ou une diminution de tolérance au glucose, l'obésité et/ou le syndrome métabolique ou la protection des cellules .beta..

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