Hiv protease inhibitors useful in the treatment of aids

Details Hiv protease inhibitors useful in the treatment of aids Hiv protease inhibitors useful in the treatment of aids

C - Chemistry, Metallurgy

07

D

C07D 217/26 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/675 (2006.01) C07C 237/20 (2006.01) C07D 207/16 (2006.01) C07D 241/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 453/02 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2161334

Compounds of formula (I), where R1 and R2 are in- dependently hydrogen or optionally-substituted C1-4alkyl or aryl, and R1 also forms a heterocycle or heterocycle-C1- 4alkyl, are HIV protease inhibitors. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds, phar- maceutically acceptable salts. pharmaceutical composition ingredients, whether or not in combination with other an- tivirals, immunomodulators, antibiotics or vaccines. Meth- ods of treating AIDS and methods of preventing or treating infection by HIV are also described.

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