C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/75 (2006.01) C12N 1/21 (2006.01) C12N 9/00 (2006.01) C12N 9/54 (2006.01) C12N 15/11 (2006.01) C12N 15/55 (2006.01)
Patent
CA 2396250
The present invention provides a mutant aprE promoter and methods for the production of a desired protein in a Bacillus host cell, which comprises the mutant aprE promoter. The present invention provides the sequence of a preferred aprE mutant promoter, which provided for a 100-fold increase in the production of a protein from Bacillus subtilis.
La présente invention concerne un promoteur d'aprE mutant et des méthodes de production d'une protéine recherchée dans une cellule hôte de bacille, comprenant ledit promoteur d'aprE mutant. L'invention concerne également la séquence d'un promoteur mutant d'aprE préféré qui multiplie par 100 la production d'une protéine de Bacillus subtilis.
Ferrari Eugenio
Valle Fernando
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Genencor International Inc.
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