Monoclonal antibody against human monocytes

Details Monoclonal antibody against human monocytes Monoclonal antibody against human monocytes

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 5/20 (2006.01)

Patent

CA 2303431

A monoclonal antibody against human monocytes which is capable of preventing the diapedesis of human monocytes after vascular endothelial cell adhesion; and hybridomas producing this antibody. This antibody is useful in clarifying the mechanism of the onset of inflammation and in diagnosing and treating inflammatory diseases.

L'invention porte sur un anticorps monoclonal contre des monocytes humains capable de prévenir la diapédèse des monocytes humains après adhésion des cellules endothéliales vasculaires, et sur des hybridomes produits par cet anticorps. Cet anticorps est utilisé dans l'élucidation du mécanisme d'apparition des inflammations et le diagnostic et le traitement de maladies inflammatoires.

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