Inhibition of phosphatidylinositol 3-kinase with wortmannin...

A - Human Necessities – 61 – K

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A61K 31/365 (2006.01) A61K 31/34 (2006.01)

Patent

CA 2128046

Abstract of the Invention Wortmannin and certain of its analogs are inhibitors of phosphatidylinositol 3-kinase. The compounds are particularly useful for inhibiting phosphatidylinositol 3-kinase in mammals and for treating phosphatidylinositol 3-kinase-dependent conditions, especially neoplasms, in mammals.

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