Indole derivatives, process for producing the same and...

Details Indole derivatives, process for producing the same and... Indole derivatives, process for producing the same and...

C - Chemistry, Metallurgy

07

D

C07D 489/09 (2006.01) A61K 31/485 (2006.01) C07D 491/20 (2006.01) C07D 491/22 (2006.01)

Patent

CA 2124455

A novel compound which is a .delta.-opioid antagonist having high selectivity and activity, that exhibits immunosuppressive action, antiallergic action, anti- inflammatory action and brain cell-protecting action is disclosed. The compound according to the present invention is an indole derivative represented by the formula (I): (see formula I) and pharmaceutically acceptable acid addition salts thereof. The present invention also provides an immunosuppressive agent, antiallergic agent, anti- inflammatory agent and brain cell-protecting agent comprising the derivative or the salt as an effective ingredient.

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