Method for producing 4-(2'-methoxyethyl) phenol

Details Method for producing 4-(2'-methoxyethyl) phenol Method for producing 4-(2'-methoxyethyl) phenol

C - Chemistry, Metallurgy

07

C

260/620.3

C07C 41/18 (2006.01) C07C 43/178 (2006.01)

Patent

CA 2036498

Abstract The invention provides a method for producing 4-(2'- methoxyethyl)phenol by brominating 4-hydroxyacetophenone to produce alpha-bromo-5-hydroxyacetophenone, and then causing a methoxide-bromide exchange to thereby produce alpha- methoxy-4-hydroxyacetophenone; and then conducting a single step reduction of alpha-methoxy-4-hydroxyacetophenone with at least two equivalents of hydrogen per equivalent of alpha-methoxy-4- hydroxyacetophenone in the presence of a hydrogenation catalyst to thereby directly produce 4-(2'-methoxyethyl)phenol.

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