Quinoline derivatives as neurokinin receptor antagonists

Details Quinoline derivatives as neurokinin receptor antagonists Quinoline derivatives as neurokinin receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 215/52 (2006.01) A61K 31/47 (2006.01) A61P 25/18 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2575936

The present invention relates to substituted quinoline-4-carboxylic acid hydrazides defined herein, pharmaceutical compositions comprising them and their use in treating diseases mediated by neurokinin-2 and/or neurokinin-3 (NK-3) receptors.

L'invention concerne des hydrasides d'acide quinoline-4-carboxylique substitués définis dans la description, ainsi que des compositions pharmaceutiques les comprenant, et leur utilisation pour traiter des maladies médiées par des récepteurs de neurokinine 2 et/ou de neurokinine 3 (NK-3).

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