New polynucleotides and polypeptides of the ifn.alpha.-17 gene

Details New polynucleotides and polypeptides of the ifn.alpha.-17 gene New polynucleotides and polypeptides of the ifn.alpha.-17 gene

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07K 14/56 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2444235

The present invention relates to new polynucleotides derived from the nucleotide sequence of the IFN.alpha.-17 gene comprising new SNPs, and new polypeptides derived from the natural wild-type IFN.alpha.-17 protein comprising at least one mutation caused by at least one SNP of the invention as well as their therapeutic uses.

La présente invention concerne de nouveaux polynucléotides dérivés de la séquence nucléotidique du gène IFN.alpha.-17 comprenant de nouveaux SNP (polymorphismes à nucléotide unique), et de nouveau polypeptides dérivés de la protéine IFN.alpha.-17 de type naturel comprenant au moins une mutation causée par au moins un SNP de cette invention ainsi que les utilisations thérapeutiques de ceux-ci.

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