Combretum laurifolium mart. extract and methods of...

A - Human Necessities – 61 – K

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A61K 36/185 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2699888

A method of inhibiting COX-2, inhibiting NF-Kappa B activation, treating inflammation, or treating cancer may comprise administering a therapeutically effective amount of an extract of Combretum laurifolium Mart. to a patient. A medicament as described herein may comprise a pharmaceutically acceptable vehicle and a therapeutically effective amount of an extract of Combretum laurifolium Mart. suspended in the vehicle. A method of making an extract of Combretum laurifolium Mart. may comprise creating a component solution by treating Combretum laurifolium Mart. material with an extractor and a solvent and producing an extract by at least partially removing liquid from the component solution. An extract of Combretum laurifolium Mart. may comprise components extracted using various solvents.

L'invention porte sur un procédé d'inhibition de COX-2, d'inhibition de l'activation de NF-Kappa B, de traitement d'une inflammation ou de traitement d'un cancer, pouvant comprendre l'administration d'une quantité thérapeutiquement efficace d'un extrait de Combretum laurifolium Mart à un patient. Un médicament tel que décrit dans la demande peut comprendre un excipient pharmaceutiquement acceptable et une quantité thérapeutiquement efficace d'un extrait de Combretum laurifolium Mart, en suspension dans l'excipient. Un procédé de fabrication d'un extrait de Combretum laurifolium Mart, peut comprendre la création d'une solution de composant par traitement d'un matériel de Combretum laurifolium Mart par un extracteur et un solvant, et la fabrication d'un extrait par le retrait au moins partiel du liquide de la solution de composant. Un extrait de Combretum laurifolium Mart peut comprendre des composants extraits à l'aide des divers solvants.

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