Novel fas ligand derivative

Details Novel fas ligand derivative Novel fas ligand derivative

C - Chemistry, Metallurgy

12

N

C12N 15/28 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) C07K 14/525 (2006.01) C12N 15/12 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2304130

This invention provides a soluble Fas ligand which functions as a Fas antagonist or an apoptosis regulator, a novel Fas ligand derivative which has excellent apoptosis--inducing activity and cytotoxic activity, and a DNA encoding such peptide.

L'invention concerne un ligand Fas soluble fonctionnant à la manière d'un antagoniste de Fas ou d'un modulateur d'apoptose; un nouveau dérivé du ligand Fas ayant une excellente activité d'inducteur d'apoptose ou cytotoxique; et un ADN codant pour le peptide.

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