A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/12 (2006.01) A61K 9/10 (2006.01)
Patent
CA 2737456
The pharmaceutical compositions described herein include a suspension which comprises an admixture in solid form of a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid and a hydrophobic medium, e.g. castor oil or glyceryl tricaprylate or a mixture thereof. The pharmaceutical compositions described herein contain medium chain fatty acid salts and are substantially free of alcohols. The pharmaceutical compositions may be encapsulated in a capsule. Methods of treating or preventing diseases by administering such compositions to affected subjects are also disclosed.
Les préparations pharmaceutiques de l'invention comprennent une suspension faite d'un adjuvant sous forme solide comprenant une quantité thérapeutiquement efficace d'un agent thérapeutique et au moins un acide gras à chaîne médiane, et un milieu hydrophobe, par exemple de l'huile de ricin ou du tricaprylate de glycéryle ou leur mélange. Lesdites préparations pharmaceutiques: contiennent des sel d'acide gras à chaîne médiane, sont sensiblement exemptes d'alcools, et peuvent être encapsulées dans des capsules. L'invention porte également sur des méthodes de traitement et de prévention de maladies par administration de telles préparations à des sujets le nécessitant.
Mamluk Roni
Marom Karen
Salama Paul
Tzabari Moshe
Weinstein Irina
Chiasma Inc.
Ridout & Maybee Llp
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