Atazanavir conjugates and antibodies useful in immunoassay

Details Atazanavir conjugates and antibodies useful in immunoassay Atazanavir conjugates and antibodies useful in immunoassay

C - Chemistry, Metallurgy

07

K

C07K 16/38 (2006.01)

Patent

CA 2586491

Activated haptens useful for generating immunogens to the HIV protease inhibitor atazanavir, immunogens useful for producing antibodies to atazanavir, and antibodies and labeled conjugates useful in immunoassays for determination of atazanavir. The haptens feature an activated functionality at the central, non-terminal hydroxyl group.

L'invention concerne des haptènes activés utiles pour générer des immunogènes entraînant une réponse par rapport à de l'atazanavir inhibiteur de la protéase du VIH, des immunogènes utiles pour produire des anticorps dirigés contre l'atazanavir, et des anticorps et des conjugués marqués utiles dans des dosages immunologiques pour déterminer l'atazanavir. Des haptènes de l'invention présentent une fonctionnalité activée sur le groupe hydroxyle non terminal central.

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