Hydrazido derivatives of hyaluronic acid

Details Hydrazido derivatives of hyaluronic acid Hydrazido derivatives of hyaluronic acid

C - Chemistry, Metallurgy

08

B

C08B 37/08 (2006.01) A61K 31/726 (2006.01)

Patent

CA 2645227

Disclosed are chemically modified hyaluronic acid (HA) derivatives containing hydrazido groups directly linked to the glucuronic acid residues of HA. Said hydrazido groups are used to obtain crosslinked and labeled HA derivatives. The invention further relates to methods of preparation of said HA derivatives.

La présente invention concerne des dérivés d'acide hyaluronique (AH) chimiquement modifiés et contenant des groupements hydrazido directement liés aux résidus acide glucuronique de AH. Lesdits groupements hydrazido sont employés pour obtenir de nouveaux dérivés de AH réticulés et marqués. La présente invention concerne également les méthodes de synthèse desdits dérivés de AH.

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