Use of nk-1 receptor antagonists for treating substance use...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/675 (2006.01) A61K 31/00 (2006.01) A61K 31/395 (2006.01) A61K 31/435 (2006.01) A61K 31/438 (2006.01) A61K 31/445 (2006.01) A61K 31/451 (2006.01) A61K 31/535 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) C07D 211/56 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2273806

The present invention provides the use of an orally active, long acting, CNS- penetrant NK-1 receptor antagonist for the manufacture of a medicament adapted for oral administration for the treatment or prevention of substance use disorders, methods of treatment using such a NK-1 receptor antagonist and pharmaceutical compositions comprising the same.

La présente invention a pour objet l'utilisation d'un antagoniste du récepteur NK-1, à action prolongée, agissant sur le système nerveux central; et à administration par voie orale, dans la fabrication d'un médicament prévu pour être administré par voie orale permettant de traiter ou de prévenir les troubles du sevrage. L'invention traite également de procédés de traitement à l'aide d'un antagoniste du récepteur NK-1 et de compositions pharmaceutiques comprenant cet antagoniste.

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