Polypeptide derivatives

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/435 (2006.01) A61K 38/04 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) A61K 51/08 (2006.01) C07C 237/22 (2006.01) C07C 243/34 (2006.01) C07C 247/22 (2006.01) C07K 1/13 (2006.01) C07K 7/04 (2006.01)

Patent

CA 2032499

A biologically active peptide selected from growth factors, peptide hormones, interferons and cytokines and analogues and derivatives thereof, and bearing at least one chelating group linked to an amino group of said peptide, the chelating group being capable of complexing a detectable element and such amino group having no significant binding affinity to target receptors, are complexed with a detectable element and are useful as a pharmaceutical, e.g. a radiopharmaceutical for in vivo imaging of target tissues or for therapy.

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