C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/02 (2006.01) A61K 31/428 (2006.01) A61K 31/437 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61P 3/00 (2006.01) A61P 7/02 (2006.01) A61P 11/06 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 21/00 (2006.01) A61P 25/00 (2006.01) A61P 27/00 (2006.01) A61P 35/00 (2006.01) A61P 37/08 (2006.01) C07D 213/26 (2006.01) C07D 213/61 (2006.01) C07D 249/12 (2006.01) C07D 277/82 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2730959
The invention relates to the novel products of formula (I): in which: Ra represents H, Hal, aryl or heteroaryl, which is optionally substituted; Rb represents H, Rc, -COORc-CO-Rc or -CO-NRcRd; where Rc represents alkyl, cycloalkyl, heterocycloalkyl, aryl and heteroaryl, all optionally substituted; Rd represents H, alk or cycloalkyl; these products being in all the isomer forms and the salts, as medicaments, in particular as MET inhibitors.
L'invention concerne les nouveaux produits de formule (I): dans laquelle : Ra représente H, Hal, aryle ou hétéroaryle éventuellement substitués; Rb représente H, Rc, -COORc,-CO-Rc ou - CO-NRcRd; avec Rc représente alkyle, cycloalkyle, hétérocycloalkyle, aryle et hétéroaryle, tous éventuellement substitués; Rd représente H, alk ou cycloalkyle; ces produits étant sous toutes les formes isomères et les sels, à titre de médicaments notamment comme inhibiteurs de MET.
Bacque Eric
Damour Dominique
Nemecek Conception
Nemecek Patrick
Wentzler Sylvie
Robic
Sanofi-Aventis
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