Separation of antithrombin iii variants by...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/81 (2006.01) G01N 27/447 (2006.01) G01N 30/02 (2006.01)

Patent

CA 2346649

A process is disclosed for the baseline separation of the AT-III variants .alpha. and .beta. which process uses a cyclodextrin-modified micellar electrokinetic chromatography. The separation is performed in the presence of a buffer solution comprising boric acid, an anionic tensid, .beta.-cyclodextrin and an aliphatic diamine.

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