Steroid modified oligonucleotides

Details Steroid modified oligonucleotides Steroid modified oligonucleotides

C - Chemistry, Metallurgy

07

H

167/191, 195/1.2

C07H 21/00 (2006.01) A61K 31/715 (2006.01) C07J 51/00 (2006.01)

Patent

CA 2033330

STEROID MODIFIED OLIGONUCLEOTIDES ABSTRACT Oligonucleotides modified at their backbones by the attachment of at least one steroid are described. The modified oligonucleotides anchor in the cell membrane to serve as a probe and to provide therapeutic activity.

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