Non-human animal with xenograft of on airway populated by...

Details Non-human animal with xenograft of on airway populated by... Non-human animal with xenograft of on airway populated by...

C - Chemistry, Metallurgy

12

N

C12N 5/08 (2006.01) A01K 67/027 (2006.01) A61L 27/38 (2006.01) C12N 5/00 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2144314

A non-human animal characterized by a human airway, the human airway being open-ended. The human airway is charac- terized by cells derived from the human respiratory system. The non-human animal and the human airway it carries are useful as models of human airways, particularly diseased human airways, for example, human CF airways. They are also useful to predict the efficacy or toxicity of agents and therapies on human airways, particularly on deseased human airways, for example, human CF airways.

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