Vaccines containing the hiv tat protein as an adjuvant for...

Details Vaccines containing the hiv tat protein as an adjuvant for... Vaccines containing the hiv tat protein as an adjuvant for...

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/39 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2542175

Tat, when used in a vaccine, causes MHC-I to expose subdominant epitopes present within an antigen, thereby enabling an optimal immune response to be generated, within an individual, against the antigen and variants of the antigen, such as might be encountered with HIV or influenza viruses.

Lorsqu'elle est employée dans un vaccin, la protéine tat amène MHC-I à exposer des épitopes sous-dominants présents dans un antigène, de telle manière qu'une réponse immunitaire optimale contre l'antigène et des variants de l'antigène, tels que l'on peut les rencontrer dans le cas du virus du HIV ou de la grippe, peut être générée chez un individu.

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