C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/093 (2006.01) A61K 38/06 (2006.01) C07C 281/10 (2006.01) C07K 5/072 (2006.01) C07K 5/078 (2006.01)
Patent
CA 2128711
Novel compounds having activity against trypsin are disclosed. Specifically, novel peptide aldehyde analogues that have substantial potency and specificity as inhibitors of mammalian pancreatic trypsin are presented. The compounds are useful in the prevention and treatment of the tissue damage or destruction associated with pancreatitis.
Brunck Terence K.
Pearson Daniel A.
Pepe Michael G.
Webb Thomas R.
Corvas International Inc.
Dendreon Corporation
Smart & Biggar
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