Pharmaceutical compositions including low dosages of...

A - Human Necessities – 61 – K

Patent

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A61K 38/00 (2006.01)

Patent

CA 2545194

The present invention is directed to a pharmaceutical composition comprising 0.5 ng to 20 ~g desmopressin and a pharmaceutically acceptable carrier. The present invention is also directed to a pharmaceutical composition comprising desmopressin and a pharmaceutically acceptable carrier, wherein the pharmaceutical composition is effective to establish a steady plasma/serum desmopressin concentration in the range of from about 0.1 picograms desmopressin per mL plasma/serum to about 10.0 picogram desmopressin per mL plasma/serum. Articles of manufacture and methods of using the above invention are also disclosed.

La présente invention concerne une composition pharmaceutique comprenant 0,5 ng à 20 ?g de desmopressine et un vecteur pharmaceutiquement admis. L'invention concerne également une composition pharmaceutique comprenant de la desmopressine et un vecteur pharmaceutiquement admis, auquel cas la composition pharmaceutique a pour effet d'établir une concentration stable de la desmopressine dans le plasma ou le sérum dans une plage comprise entre 0,1 et 10 picogrammes de desmopressine par millilitre de plasma ou de sérum. L'invention concerne enfin des produits manufacturés et des procédés permettant d'utiliser l'invention.

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