Pharmaceutical compositions comprising lercanidipine

Details Pharmaceutical compositions comprising lercanidipine Pharmaceutical compositions comprising lercanidipine

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/4418 (2006.01)

Patent

CA 2547657

A controlled release pharmaceutical composition comprising lercanidipine dissolved or dispersed in a solid vehicle at ambient temperature, thus forming a solid dispersion, achieves delayed release of lercanidipine over an extended period of time, reduced food effect and increased bioavailability compared to commercially available lercanidipine containing products.

L'invention concerne une composition pharmaceutique à libération contrôlée comprenant de la lercanidipine dissoute ou dispersée dans un excipient solide à température ambiante, formant ainsi une dispersion solide. Ladite composition permet d'obtenir une libération retardée de lercanidipine sur une durée prolongée, un effet alimentaire réduit et une biodisponibilité accrue comparé aux produits contenant de la lercanidipine disponibles dans le commerce.

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