Heteroaromatic monoamides as orexinin receptor antagonists

Details Heteroaromatic monoamides as orexinin receptor antagonists Heteroaromatic monoamides as orexinin receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 213/40 (2006.01) A61K 31/44 (2006.01) A61K 31/4406 (2006.01) C07D 213/56 (2006.01) C07D 213/75 (2006.01) C07D 215/38 (2006.01) C07D 231/40 (2006.01) C07D 261/08 (2006.01) C07D 277/46 (2006.01) C07D 333/20 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07K 5/02 (2006.01)

Patent

CA 2726703

The present invention is concerned with novel sulfonamides of formula I wherein R1, R2, R3, R4, R5 Ar, Ar1, Ar2, n, o and p are as described in the description and claims. The compounds are orexin receptor antagonists may be useful in the treatment of disorders, in which orexin pathways are involved.

La présente invention concerne de nouveaux sulfonamides répondant à la formule I, dans laquelle R1, R2, R3, R4, R5, Ar, Ar1, Ar2, n, o et p sont tels que décrit dans la description et les revendications. Les composés sont des antagonistes des récepteurs de lorexine qui peuvent être utiles pour le traitement daffections, dans lesquelles les voies de lorexine peuvent jouer un rôle.

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