Homo-prostaglandin derivatives as ocular hypotensives

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 405/00 (2006.01) A61K 31/557 (2006.01) C07D 307/34 (2006.01) C07D 333/04 (2006.01)

Patent

CA 2096944

2096944 9210193 PCTABS00013 The invention relates to homo-prostaglandin derivatives. More particularly, the present invention concerns 1a-homo derivatives of naturally occurring and synthetic prostaglandins, the corresponding bis- and trishomo-prostaglandin compounds, and their 1-esters and salts. The homo-prostaglandin compounds of the present invention are potent ocular hypotensives, and are particularly suitable for the management of glaucoma.

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